The toolkit · For teens · For parents · For providers & educators

POTS vs. Anxiety

A quick-reference chart for teen girls, families, educators, and healthcare providers to tell autonomic dysfunction (POTS) apart from psychological anxiety and panic attacks.

The comparison

6 things to look at when a racing heart gets called a panic attack. The pattern of the symptoms, not the symptoms themselves, is what separates them.

FeaturePOTS (Postural Orthostatic Tachycardia Syndrome)Anxiety or panic attack
Primary triggerPOTSPhysical: moving from lying or sitting to standing, or standing still for extended periods.Anxiety or panicPsychological: stressful thoughts, sensory overload, environments, or emotional triggers.
Heart rate patternPOTSSpikes by 30+ BPM (or exceeds 120 BPM) specifically upon standing; usually settles when lying flat.Anxiety or panicSustained high heart rate regardless of physical position (sitting, standing, or lying down).
Positional reliefPOTSImmediate and significant: symptoms improve rapidly within minutes of lying down or elevating the legs.Anxiety or panicMinimal to none: lying down does not automatically resolve the elevated heart rate or panic.
Physical signsPOTSBlood pooling in legs and hands (purple or mottled skin), "coat hanger" neck and shoulder pain, cold hands and feet.Anxiety or panicSudden facial flushing, generalized heat, sweating, tremors, or hyperventilation.
RecoveryPOTSSymptoms usually improve significantly within minutes of lying down; hydration and salt are known to help.Anxiety or panicSymptoms persist until the emotional stressor fades or self-soothing techniques take effect.
Underlying mechanism (the "why")POTSFailure of the Autonomic Nervous System (ANS) to properly constrict blood vessels against gravity.Anxiety or panicActivation of the body's adrenaline, or "fight-or-flight," pathway, triggered by the brain's amygdala.

How to use this chart

In clinical appointments

When a physician suggests a postural heart rate spike is "just anxiety," use this response:

My heart rate consistently increases by over 30 beats per minute specifically when I stand up, and it drops immediately when I lie flat. Because this symptom is strictly positional and tied to postural changes rather than emotional stressors, I would like to request an evaluation or tilt-table test for postural dysautonomia.

For educators and school health personnel

When a student presents with sudden fatigue, lightheadedness, or a rapid pulse in class: